


Canine Flex Support – Chewable Joint Health Wafers with Glucosamine, Chondroitin for Dogs
What Canine Flex Support Is & Its Benefits
Canine Flex Support is a chewable wafer formula for dogs, brimming with glucosamine sulfate and chondroitin sulfate, designed to support healthy joint function and cartilage health—especially useful for active or aging pups.
Key benefits include:
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Supporting the body’s normal inflammatory response
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Maintaining healthy joint pathways and cartilage support
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Delivering antioxidant vitamins A and C
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Encouraging healthy immune system function
Ideal for: Large breeds, performance dogs, growing puppies, or any pooch needing joint support.
100 Wafers per bottle.
Ingredients & Guaranteed Analysis
Each 1-wafer serving contains:
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Glucosamine sulfate (from shellfish) – ≥ 250 mg
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Chondroitin sulfate – ≥ 110 mg
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Vitamin E (as d‑alpha tocopherol, sunflower) – ≥ 5 IU
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Vitamin C (ascorbic acid) – ≥ 5 mg
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Plus: ginger root, honey, bovine liver, calcium stearate, modified tapioca starch, turmeric powder
Usage Directions (By Weight Tier)
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1–25 lbs: 1 wafer/day
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26–50 lbs: 2 wafers/day
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51–80 lbs: 3 wafers/day
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Over 80 lbs: 4 wafers/day
Guaranteed Analysis:
Vitamin E (min) 5 IU / wafer
Ascorbic Acid (Vitamin C)* (min) 5 mg / wafer
Chondroitin (as chondroitin sulfate)* (min) 110 mg / wafer
Glucosamine Sulfate (from shellfish)* (min) 250 mg / wafer
*Not recognized as an essential nutrient by the AAFCO Dog Food Nutrient Profile

Ingredient highlights

Research on glucosamine and chondroitin for dog joint healt
Glucosamine (for dogs):
Glucosamine supplies raw material for glycosaminoglycans and proteoglycans—the “cushion” inside cartilage—supporting joint lubrication and structural repair. In client-owned dogs with hip/elbow OA, a randomized double-blind trial (n=35) found an oral glucosamine HCl + chondroitin combo significantly improved veterinarian-scored pain, weight-bearing, and overall severity by about 10 weeks, albeit with slower onset than carprofen. Newer block-randomized work in 75 dogs didn’t see force-plate improvement at 6 weeks with glucosamine/chondroitin vs placebo, suggesting benefits (when they occur) may require a longer run-in and remain modest—consistent with reviews that call the evidence mixed but biologically plausible and generally safe. PubMedFrontiersPMC
Chondroitin (for dogs):
Chondroitin sulfate helps cartilage retain water, supports proteoglycan synthesis, and can down-regulate catabolic enzymes that chew up matrix. In an experimental canine OA model, an oral chondroitin + glucosamine + manganeseregimen shifted synovial fluid 3B3/7D4 epitopes—biomarkers consistent with enhanced cartilage matrix metabolism—supporting a chondroprotective effect; and in client-owned dogs, the glucosamine/chondroitin combo improved clinical scores by ~10 weeks in an RCT. Contemporary veterinary reviews judge effects as possible but variable across trials (small when present), with a favorable tolerability profile. PubMed+1MDPI
Sources
- McCarthy G et al. Vet J. 2007: Randomised double-blind, positive-controlled trial of oral glucosamine HCl + chondroitin in dogs with OA (improvement by day 70). PubMed
- Kampa N et al. Front Vet Sci. 2023: Block-randomized, double-blinded, placebo-controlled trial; glucosamine/chondroitin not superior to placebo at 6 weeks on PVF. Frontiers
- Johnson KA et al. Osteoarthritis & Cartilage 2001: CS-G-M altered synovial fluid epitope biomarkers (3B3/7D4) in a canine OA model. PubMed
- Bhathal A et al. Open Vet J. 2017: Narrative review—use common, biologic rationale plausible, clinical efficacy mixed. PMC
- Fernández-Martín S et al. Animals (MDPI) 2021: Review—mechanisms for glucosamine/chondroitin in companion-animal OA; evidence remains controversial.