Vitamin D3 + K2 Supplement by Metagenics for Bone, Heart, and Immune Health

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Metagenics Vitamin D3 5000 with K2 – High Potency Support for Bones, Hormones & Immunity

Reclaim your health at any age—especially during menopause.
Vitamin D isn’t just a vitamin—it’s a prohormone that regulates hundreds of processes in your body. Metagenics Vitamin D3 5000 with K2 delivers bioactive D3 plus clinically effective vitamin K2 (menaquinone-7) to support healthy calcium metabolism, strong bones, immune resilience, and cardiovascular protection.*

This powerful combo is especially critical for women during perimenopause and menopause, when estrogen declines can weaken bone density and disrupt hormonal balance. Vitamin D3 boosts calcium absorption, while K2 ensures it gets deposited in your bones—not your arteries.*

Key Benefits:

✅ Supports healthy bone density and calcium absorption*
✅ Aids in hormone balance during menopause and aging*
✅ Promotes immune function and inflammation response*
✅ Protects cardiovascular health by directing calcium to bones*
✅ Helps mood, energy, and neuromuscular function*

Why D3 + K2 Together?
Vitamin D gets calcium into your bloodstream. Vitamin K2 tells it where to go. Without K2, calcium can accumulate in your arteries—leading to plaque buildup. This formula pairs 5,000 IU of D3 with 180 mcg of K2 for safe, effective results.

Who It’s For:

  • Women in perimenopause or menopause

  • Anyone with low vitamin D levels

  • Those avoiding sun exposure

  • Individuals at risk for osteoporosis, heart disease, or immune challenges

Suggested Use:
Take 1 softgel daily with a meal, or as directed by your healthcare provider.

Vitamin D3 + K2 Premier – FAQs

What is Vitamin D3 + K2 and how do D3 and K2 work together for bone strength and calcium metabolism?

Vitamin D3 + K2 Premier pairs vitamin D3 (cholecalciferol) for calcium absorption with vitamin K2 (often MK-7) to direct calcium into bones and teeth. Together they support bone strength, healthy calcium metabolism, and everyday musculoskeletal health.

How does Vitamin D3 + K2 support vascular health and proper calcium placement?

D3 + K2 for vascular health supports proteins that help keep calcium where you want it (skeletal tissue) and away from where you don’t (soft tissues). It’s a smart combo for arterial health alongside diet and exercise.

Why choose vitamin K2 MK-7 instead of vitamin K1 or MK-4?

K2 MK-7 has a longer half-life than K1 and MK-4, supporting steady activation of vitamin-K–dependent proteins involved in bone density and vascular integrity. Check this page’s Supplement Facts for the exact K2 form and potency.

What’s the best Vitamin D3 + K2 dosage and when should I take it for absorption?

Follow the label for your D3 + K2 dosage. Take with a meal that contains healthy fats to support fat-soluble vitamin absorption. Consistency beats megadoses—stick to a daily rhythm.

Can I combine Vitamin D3 + K2 with calcium, magnesium, or collagen for bone health?

Yes—many pair D3 + K2 with calcium, magnesium, and sometimes collagen to round out a bone health stack. Space minerals away from thyroid meds or certain antibiotics per your clinician’s advice.

Who should talk to a clinician before using Vitamin D3 + K2?

Consult your provider if you’re on anticoagulants (e.g., warfarin), have hypercalcemia, kidney disease, parathyroid disorders, are pregnant or nursing, or have any medical condition requiring supervised vitamin D use.

How long until I notice benefits and which labs should I monitor?

Evaluate over 4–12 weeks. Your clinician may check 25-hydroxyvitamin D [25(OH)D] and, when relevant, calcium and related markers to personalize your vitamin D3 status and dose.

Is this Vitamin D3 + K2 Premier supplement non-GMO and suitable for special diets?

Review the Supplement Facts and ingredient list for excipients and allergen info. Many shoppers look for non-GMO, gluten-conscious, and vegetarian-friendly D3/K2 (note: some D3 sources are lanolin-derived).