Zypan® – HCL and Digestive Enzyme Support for Protein and pH Balance

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Enhance your digestive power with Zypan®, a clinically formulated blend of pancreatin, pepsin, and betaine hydrochloride designed to support healthy digestion, protein breakdown, and optimal gastric pH. Whether you're dealing with sluggish digestion, bloating, or protein-heavy meals, Zypan® helps restore the ideal environment for macronutrient breakdown and GI health at the source.*


🍽️ What It Supports:

  • Protein digestion through enzymatic activity (pepsin + pancreatin)*

  • Stomach acid support with betaine HCl for improved gastric pH*

  • Macronutrient breakdown (fats, proteins, carbohydrates)*

  • GI tract environment optimized for nutrient absorption and microbiome balance*


🧪 How It Works:

Zypan® uses a targeted enzyme blend:

  • Pancreatin (includes protease, amylase, and lipase) to support complete macronutrient digestion*

  • Pepsin to help break down protein in the stomach*

  • Betaine Hydrochloride (HCl) to support gastric acid levels necessary for enzyme activation and nutrient absorption*

The stearic acid coating ensures the pancreatin is delivered to the correct area of the digestive tract, avoiding premature breakdown in the stomach.


💊 Suggested Use:

Take as directed by your healthcare practitioner. Common protocols involve 1–2 tablets with meals, particularly protein-rich meals.


🌿 Why Choose Zypan®?

  • Combines enzymatic and acid support for comprehensive digestion

  • Ideal for individuals with low stomach acid or difficulty digesting proteins

  • Supports better nutrient absorption, gut balance, and less post-meal discomfort*

  • Backed by decades of clinical use in functional and integrative practices


⚠️ Who Might Benefit:

  • Individuals with bloating, fullness, or slow digestion*

  • Those over age 40 or under chronic stress (when HCl naturally declines)*

  • People on high-protein diets or with digestive insufficiency*

Zypan – FAQs

What is Zypan and how does this digestive enzyme dietary supplement support digestion?

Zypan digestive enzyme is formulated to support healthy stomach acid and digestive enzyme activity, promoting comfortable breakdown of proteins, fats, and carbohydrates for everyday gut comfort after meals.

Which enzymes are in Zypan and what do they do?

Digestive enzyme formulas commonly include proteases for protein, lipases for fats, and amylases for carbs. Many Zypan users look for enzymes such as pancreatin or pepsin; check this page’s Supplement Facts for the exact enzyme profile and potencies.

Does Zypan include betaine HCl and why is stomach acid support important?

Many choose a digestive enzyme with betaine HCl to support normal gastric acidity, which helps activate enzymes and promote efficient protein digestion. Review the label here to confirm betaine HCl content per serving.

How should I take Zypan—dosage, timing, and with meals?

Follow the Zypan dosage on the label. Enzymes are typically taken at the start of meals (or split during the meal). Start with the suggested amount; adjust with practitioner guidance based on meal size and comfort.

Can Zypan help with occasional bloating, gas, or a “heavy” feeling after meals?

Digestive enzyme supplements like Zypan are used to support efficient macronutrient breakdown, which can help maintain post-meal comfort and reduce the “too-full” feeling from larger or richer meals.

Who should not use betaine HCl or acid-support formulas?

Avoid betaine HCl if you have active or history of ulcers, gastritis, reflux sensitivity, or if you’re using acid-suppressing medications (PPIs/H2 blockers) unless directed by your clinician. If you experience burning or discomfort, discontinue and seek professional advice.

Can I combine Zypan with probiotics, bile salts, or digestive bitters?

Yes—some people pair Zypan digestive enzymes with probiotics, prebiotic fiber, bile support, or digestive bitters for a comprehensive gut routine. If you take prescriptions or have conditions, check with your healthcare professional.

Is Zypan vegetarian and free of common allergens?

Review the Supplement Facts and ingredient list for potential allergens and whether enzymes are animal-derived (some pancreatin/pepsin sources are not vegetarian). Many shoppers look for non-GMO and gluten-conscious formulas—verify the label or contact support if you have sensitivities.